A variety of transdermal and epidermal sensors are currently under development in both academic and industrial settings, demonstrating that wearable biosensing is a promising technology with extraordinary commercial potential. But there are still many challenges and technological gaps to overcome in order to expand the field of molecular body monitoring technology beyond the already established continuous glucose sensing. Many of these critical limitations relate to invasiveness, poor biocompatibility, limited lifetime, low sensitivity and poor selectivity and are directly related to the design of the biosensor.

We want to develop a skin patch capable of detecting transdermal levels of various compounds (cortisol as an indicator of stress, insulin for diabetics, lactate for athletes, serotonin for depression). The biosensor patch should be integrated into a microneedle platform that will act as an electrochemical transducer while allowing painless access to interstitial fluids, thus moving towards non-invasive, quantitative and objective monitoring of various health-related parameters.